Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse model
نویسندگان
چکیده
منابع مشابه
Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse model.
OBJECTIVES With the isolation of clinical strains of Staphylococcus aureus carrying the gene that confers vancomycin resistance, the need for novel antistaphylococcals has become more urgent. Lysostaphin, an example of such a novel therapeutic, is an endopeptidase that rapidly lyses S. aureus through proteolysis of the staphylococcal cell wall. We evaluated its efficacy as a therapeutic agent f...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2007
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkm347